Patient safety is at the core of ASA’s vision and values. Therefore, the American Society of Anesthesiologists believes that as vaccines against SARS-CoV-2 (the virus that causes COVID-19) become available that are recommended by the scientific community and FDA-approved, early access to vaccination should be provided to people at greatest risk for severe illness. This subdivision of the population, documented by multiple studies identifying risk factors for mortality following infection with SARS-CoV-2, needs to be protected as urgently as possible.